616-30-8

  • Product Name:3-Amino-1,2-propanediol
  • Molecular Formula:C3H9NO2
  • Purity:99%
  • Molecular Weight:91.11
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Product Details;

CasNo: 616-30-8

Molecular Formula: C3H9NO2

Appearance: clear colorless to pale yellow viscous liquid

3-Amino-1,2-propanediol Good Supplier In Bulk Supply High Purity 616-30-8

  • Molecular Formula:C3H9NO2
  • Molecular Weight:91.11
  • Appearance/Colour:clear colorless to pale yellow viscous liquid 
  • Vapor Pressure:0.00116mmHg at 25°C 
  • Melting Point:55-57 °C 
  • Refractive Index:n20/D 1.492(lit.)  
  • Boiling Point:266.7 °C at 760 mmHg 
  • PKA:12.11±0.35(Predicted) 
  • Flash Point:115.1 °C 
  • PSA:66.48000 
  • Density:1.181 g/cm3 
  • LogP:-1.00140 

3-Amino-1,2-propanediol(Cas 616-30-8) Usage

Preparation

3-Amino-1,2-propanediol is synthesized by reacting 3-chloro-1,2-propanediol (CPD) with ammonia in alkaline environment by adding sodium hydroxide. Afterwards, the product undergoes a series of purification steps.

Application

(±)-3-Amino-1,2-propanediol is used as a reactant in the synthesis of lipid-like delivery molecules(lipidoids) for RNA interference (RNAi) therapeutics. It is also used in the synthesis of the bioactive template to prepare cationic α-helical polypeptides and various cationic polymers for gene delivery.

Brand name

Aminomux

InChI:InChI=1/C3H9NO2/c4-1-3(6)2-5/h3,5-6H,1-2,4H2/p+1/t3-/m1/s1

616-30-8 Relevant articles

COMPLEX OF GADOLINIUM AND A CHELATING LIGAND DERIVED FROM A DIASTEREOISOMERICALLY ENRICHED PCTA AND PREPARATION AND PURIFICATION PROCESS

-

Paragraph 0027-0028, (2021/12/03)

The present invention relates to a compl...

PROCESS FOR THE HYDROLYSIS OR ALCOHOLYSIS OF CYCLIC KETAL OR ACETAL GROUPS WITH CARBON DIOXIDE OR AN ALCOHOL

-

Page/Page column 7, (2019/02/13)

Process for the hydrolysis or alcoholysi...

PROCESS FOR THE PREPARATION OF A 3-AMINO-1,2-PROPANDIOL AND DERIVATIVES THEREOF

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Page/Page column 9; 10, (2019/02/13)

Process for the preparation of a compoun...

Production of Primary Amines by Reductive Amination of Biomass-Derived Aldehydes/Ketones

Liang, Guanfeng,Wang, Aiqin,Li, Lin,Xu, Gang,Yan, Ning,Zhang, Tao

supporting information, p. 3050 - 3054 (2017/03/14)

Transformation of biomass into valuable ...

616-30-8 Process route

3-monochloro-1,2-propanediol
96-24-2

3-monochloro-1,2-propanediol

3-Amino-1,2-propanediol
616-30-8,13552-31-3,98923-21-8

3-Amino-1,2-propanediol

Conditions
Conditions Yield
With ammonia; sodium hydroxide; In water; at 18 - 42 ℃; for 0.399667h;
67.4%
With sodium hydroxide; ammonia; water;
 
With potassium hydroxide; ammonia; In methanol;
 
With ammonium hydroxide; hydroquinone; N-nitrosodiphenylamine; In ethanol; at 45 - 60 ℃; for 4h; under 1125.11 - 1650.17 Torr; Large scale;
 
Glyceraldehyde
56-82-6,367-47-5,26793-98-6

Glyceraldehyde

3-Amino-1,2-propanediol
616-30-8,13552-31-3,98923-21-8

3-Amino-1,2-propanediol

Conditions
Conditions Yield
With ammonia; active charcoal; palladium; In water;
94.5%
With ammonium hydroxide; hydrogen; at 55 ℃; for 6h; under 15001.5 Torr; Autoclave; Green chemistry;
 

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